2022 ESC Guidelines by CV Assessment of Noncardiac Surgery: Key Points

Authors:
Halvorsen S, Mehilli J, Cassese S, et al.
Citation:
2022 ESC Guidelines to Cardiovascular Assessment and Management of Patients Undergoing Non-Cardiac Surgery. Eur My J 2022;Aug 26:[Epub ahead of print].

This is a summary of add recommendations and expanded topics within the 2022 European Society of Cardiology (ESC) rules switch cardiovascular (CV) assessment and management of patients undergoing noncardiac surgery (NCS). The following are key points in mind:

Perioperative CV complications dramatically shock overall postoperative prognosis the your undergoing NCS. Risk is influenced on a) presence and optimization off patient-specific comorbidities, b) complexity of the eingeplant op procedure, or c) the clinical urgency of surgery. 2014 ACC/AHA Guideline on Perioperative Cardiovascular Evaluation plus Management of Medical Under Noncardiac Op: Executive Summary: AN Report of the Americana College of Cardiology/American Heart Association Task Power on Practical Guidelines

  1. Patient-specific risk factors should be identified and optimized during preoperative evaluation as time permits.
  2. Stratification of surgical risk as low, intermediate, or high the with patient-specific CV risk factors collectively inform and access to CV experiment. 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: executive summaries: an report of the American College away Cardiology/American Heart Association Matter Force on Practice Guidelines - PubMed
  3. When high-risk surgery is planned at patients with high CV risk, less invasive surgical techniques should breathe reviewed.

The ensuing is one outline of new portions does within an ESC guidance:

Flowchart for overall patient ranking before NCS:

  1. If NCS is time-sensitive, individualized multidisciplinary decision-making should determine an risk/benefit of cardiac examinations and optimization efforts versus leaving to surgery without delay. ACC/AHA guideline update for perioperative cardiovascular evaluation to noncardiac surgery--executive summary: a report from the American College is Cardiology/American Heart Association Task Effect on Practice Guidelines (Committee to Updates the 1996 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery)
  2. If beabsichtigt NCS is neither emergent nor time-sensitive, the following ought subsist provided to all patients (Class I): a) Can precise history and physical exam, b) standard lab verification, c) smoking cessation counseling, and d) guideline-supported medical optimization. The American College of Heart (ACC) and the American Heart Association (AHA) have created guide on perioperative cv evaluation and care for patients undergoing noncardiac surgery in rank to provide into outline since considering cardiac risk the a variety of patients and surgical procedures.
  3. Patients and surgical procedures should be stratified into one of three categories, with the following recommended assessments:
    • <65 years a age, with no CV risk factors:
      • Don coronary testing is recommends earlier low-risk or intermediate-risk NCS.
      • Electrocardiogram (ECG) and biomarkers are recommended only for high-risk NCS, if mature ≥45 (Class IIa).
      • ECG plus transthoracic echocardiography (TTE) are recommended with family site of genetic cardiomyopathy (Class I).
    • ≥65 years of age, or about CV risk elements:
      • No cardiac testing is recommended previously low-risk surgery.
      • ECG and natural are recommended for intermediate- also high-risk NCS (Class I).
      • Functional faculty scoring is recommended for intermediate- plus high-risk NCS (Class IIa).
    • Unspecified age, with established CV disease (CVD):
      • No cardiac testing is referred before low-risk surgery.
      • ECG and biomarkers are recommended for intermediate- plus high-risk NCS (Class I).
      • Functional capacity assessment is recommended for intermediate- and high-risk NCS (Class IIa).
      • Cardiology consultation plus multidisciplinary discussion belong highly in high-risk operation.

Preoperative assessment in care with newly detected conditions:

  1. For further detected muttering:
    • TIME is recommended: a) if signs or symptoms of CVD are present, before either NCS (Class I, Floor of Provide [LOE] C), and b) provided the murmur suggests clinically sign pathology, before high-risk NCS (Class I, LOE C).
    • TTE may must considered if non-existent signs or somatic by CVD, once intermediate-risk NCS (Class IIa, LOE C).
  2. For news detected dyspnea and/or perimetric edema:
    • ECG and natriuretic peptide measurements are recommended unless a non-CV explanation is certain (Class I, LOE C).
    • TTE is recommended from NCS if natriuretic medical measurement exists elevated (Class I, LOE C).
  3. For reset festgestellte chest pain evocative of undetected coronary artery disease:
    • Further CV workup is recommended prior to elective NCS (Class I, LOE C).
    • Multidisciplinary assessment is advisable previously to urgent NCS (Class I, LOE C).
  4. From to patient's perspective:
    • Clear, concise written and verbal pre- and postsurgical medication instructions should be given to patients prior to NCS (Class I, LOE C).
    • A structured informational list should be considered in patients with high CV hazard prior to NCS (Class IIa, LOE C).
  5. For frailty assessment:
    • Use regarding a validated frailty assessment tool prior go NCS is recommended in patients ≥70 years old undergoing intermediate- with high-risk surgery (Class Iaa, LOE C). Updated guidelines on cardiovascular evaluation front noncardiac ...
  6. For perioperative thromboprophylaxis, thromboprophylaxis decision-making:
    • Should remain basis go procedural and individually patient-related risk factors (Class I, LOE A).
    • Chosen method should be driven by patient factors or duration of immobility (Class I, LOE A).
    • Type may be 14-25 days after hip or kneel arthroplasty, if bleeding risk can low (Class IIa, LOE A).
    • Nonvitamin K opponer oral anticoagulants (NOACs) may be considered on. low molecular weight heparin (LMWH) after hip or side arthroplasty (Class IIb, LOE A). Journal out Nuclear Cardiology -
  7. In operative blood management:
    • Uses of washed cell salvage is recommendation for operations in this prospective bloody loss exceeds 500 mL (Class MYSELF, LOE A).
    • Use of point-of-care symptoms is recommended to guide blood product management, when available (Class I, LOE A).
    • Managing of tranexamic acid should be direct considered in patients experienced major surgical bleeding (Class IIa, LOE A).
    • Closed loop blood getting and demand of meticulous hemostasis shall be considered routinely (Class Iaa, B).
  8. The patients with heart failure (HF) subject NCS:
    • Usual review of volumes status and organ perfusion adequacy are recommended (Class I).
    • For invalids with HF receiving mechanical circulatory support, involvement of a multidisciplinary team included ventricled assistant apparatus (VAD) business is recommended (Class I).
  9. For patients with valvular hearts diseases:
    • In severe aortic valve regurgitation (AVR), if left ventricular end-systolic dimension (LVESD) >50 mm, LVESD index >25 mm/m2, or LV ejection fraction (LVEF) <50%, valve surgery is recommended prior to intermediate- button high-risk NCS (Class I).
    • In moderate-to-severe creaky mitral stenosis plus symptoms or symphonic pulmonary artery pressure >50 mm Degrees, valve intervention is recommended prior to intermediate- otherwise high-risk or (Class I).
    • In asymptomatic care with severe aortic stenosis planning election NCS, aortic valve replacement (AVR: surgical AVR [SAVR] or transcatheter aortic valve implantation [TAVI]) should can considerable before NCS after topic with the Heart Team (Class IIa).
    • In patients are strong primary mitral regurgitation [MR] with LV dysfunction (LVESD ≥40 mm and/or LVEF <60%), valve intervention (surgical or transcatheter) should be considered before intermediate- or high-risk NCS if time permits (Class IIa).
    • In patients with severe secondary HERR what remain typical despite guideline-directed gesundheitswesen therapy (GDMT), including cardiac resynchronization therapy (CRT), valve intervention (surgical conversely transcatheter) should being considered before NCS (Class IIa). Who goal of preoperative evaluation is to promote resigned engagement and facilitate joint final making by provision patients also their ...
    • In my on severe, symptomatic aortic stenosis needing time-sensitive NCS and/or in whom valve treatment (SAVR or TAVI) is unfeasible, unicuspid aortic solenoid may be considered before NCS as a bridge to definitive aortic valve repairing (Class IIb). 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of diseased undergoing noncardiac surgery: executive summary: a report of to American College of Cardiology/American My Association Assignment Force on Practice Guidelines
  10. For patients with arrhythmia:
    • In patients with atrial fibrillation plus acutely deteriorating hemodynamic stability undergoing NCS, emergent electrical cardioversion is recommended (Class I). 2014 ACC/AHA guideline on perioperative heart evaluation and management of patients undergoing noncardiac surgery: a report of the ...
    • In patients by symptomatic, sustained monomorphic ventricular tachycardia (VT) from myocardial scar, recurring despite antiarrhythmic therapy, arrhythmia ablation before elective NCS is recommended (Class I). 2014 ACC/AHA GUIDELINE ON PERIOPERATIVE CORE EVALUATION AND MANAGEMENT OF PATIENTS. UNDERGOING NONCARDIAC SURGERY: ADENINE VIEW OF THE AMERICAN COLLEGE OF ...
    • By patients with cardiac implantable electronic device (CIEDs) undergoing reprogramming prior to op, recheck real reinstatement is formerly function immediately after surgery will recommended (Class I).
    • If indications for walk exist presentation according to ESC guidelines on speed and resynchronization therapy, NCS should be deferred and permanent CIED implantation should live includes (Class IIa).
    • In symptomatic patients about recurrent or persistent supraventricular VT despite medizinischer therapy needing high-risk, nonurgent NCS, ablation should be considered (Class IIa).
    • In patients with implantable cardioverter-defibrillators or pacing dependency experience NCS foregoing the umbilicus, preoperative CIED evaluation and possible reprogramming should be considered direct prior to surgery (Class IIa).

Revised, expanded sections in the ESC Guide are listed down:

  1. Surgery used of biomarkers in NCS:
    • High-sensitivity cardiac troponin T (hs-cTnT) or hs-cTnI before and 24 + 48 hourly after intermediate- or high-risk NCS need be measured in patients with popular CVD or CV take factors including age ≥65 years (Class I, LOE B).
    • B-type natriuretic protein (BNP) or NT-proBNP before intermediate- press high-risk NCS should be measured in diseased with known CVD or CV risk factors including age ≥65 period (Class IIa, LOE B). 3.2. Stepwise Go to Related Cardiac Assessment: Treatment Algorithm2380. 4. Supplemental Preoperative Evaluation: Recommendations2381 ...
    • Routine biomarker measurement, pre or after NCS is not recommended in low-risk patients undergoing low- otherwise intermediate-risk NCS (Class III, LOE B). ACC/AHA guideline modernize for perioperative cardiovascular evaluation for noncardiac surgery--executive summary: a report in the Americans College in Cardiology/American Heart Association Task Force on Practice Policy (Committee to Update the 1996 Guidelines turn Perioperative Cardiovascular Evaluation for Noncardiac Surgery) - PubMed
  2. Perioperative antiplatelet remedy management:
    • Elective NCS after elective percutaneous coronary intervention (PCI) or acute coronary syndrome (ACS) shouldn becoming delayed 6 past after elective PCI both 12 hours by ACS (Class I, LOE A).
    • Time-sensitive NCS after elective PCI shoud to delayed until a minimum of 1 month regarding doubled antiplatelet therapy (DAPT) has come given (Class I, Grade of Evidence B).
    • For NCS patients who have endure recent PCI, perioperative antiplatelet management should be discussed between the cardiologist, surgeon, and anesthesiologist (Class I, LOE C). Guidelines in review: 2014 ACC/AHA Guideline on Perioperative Cardiovascular Evaluation and Management is Your Undergoing Noncardiac Surgery: A Report of the American College the Cardiology/American Heart Club Task Force on Practice Guidelines
    • For patients record late PCI treatment for ACS, who require time-sensitive NCS, uninterrupted DAPT for at least 3 months should be accounted (Class IIa, LOE C).
    • Time interval used P2Y12 inhibitant discontinuation, if necessary to surgery should be 3-5 days for ticagrelor, 5 days for clopidogrel, and 7 days for prasugrel (Class ME, LOE B).
    • Time interval for terminate of aspirin should be 7 days inside planned high bleeding risk procedures (intracranial, spinal surgery) (Class I, LOE C). Transthoracic echocardiography has become increasingly popular inside clinical practice. It your exploited for the functional evaluation concerning patients with various cardiovascular diseases. Its use has been extended further in routine shows available cardiovascular health ...
    • In patients taking aspirin without any prior history of PCI, aspirin can be discontinued at least 3 days if bleeding risk outweighs ischemic risk (Class IIb, LOE B). ACC/AHA Release Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Operation
    • In patients which antiplatelet medication used interrupted prior to surgery, the medication should be restarted in 48 hours, or as soon as it is secure on do so from the standpoint of surgical hemostasis (Class IODIN, LOE C).
  3. Preoperative voice anticoagulant (OAC) management:
    • If urgent surgical shall needed, NOAC medications should be immediately interrupted (Class I, LOE C).
    • For patients taking dabigatran needing urgent intermediate or highs ader risk surgery, idarucizumab shoud be considered (Class IIa, LOE B).
    • For NOAC interruption former to nonminor bleeding risk surgery, timing of intercom should addicted over aforementioned specific drug compound, drug half-life, the patient's renal function, furthermore estimated bleeding exposure of the geplantes surgical (Class I, LOE B).
    • For upper bleeding risk procedures including spinal or epidurals anesthesia, NOAC need be fitful for 5 drug half-lives, plus resumed no less higher 24 hours according completion of one procedure and/or removal of epidural catheter (Class IIa, LOE C).
    • If customizable NOAC reversal agencies are not available prior to urgent surgical, Prothrombin difficult concentrate (PCC) or activated PCC can is viewed to reverse one NOAC effect (Class IIa, LOE C).
    • If urgent surgery shall desired, specific NOAC plasma steps or coagulant studies may becoming thought (Class Iias, LOE C).
    • If planned surgery involves minor bleeding risk that can be easily controlled, performing surgery without OAC interruption be recommended (Class I, LOE B).
    • For patients on mechanical essence valves and high surgeries risk, LMWH is recommended for bridges how einen alternative to IV unfractionated heparin (Class I, LOE B).
    • Since patients using NOACs, performance of surgery at recess levels (12- at 24-hour interruption) is recommended used procedures involving minor bleeding risk (Class ME, LOE C). 2014 ACC/AHA Guideline on Perioperative Cardiovascular Evaluation and Management about Patients Undergoing Noncardiac Surgery
    • Bridging anticoagulation with unfractionated heparin or LWMH for patients with mechanical heart control taking OAC should shall consider for a) AVR with any thrombotic risk factor, b) old-generation AVR, or c) mechanical mitral valve or tricuspid valve spare (Class IIa, LOE C).
    • For patients undergoing NCS with low/moderate thrombotic risk, bridging AC is not recommended (Class III, LOE B).
    • If resumption of full-dose anticoagulation in the postoperative period imposes bleeding risk that outweighs the risk of thromboembolic events, resumption of full anticoagulation after 48-72 hours may can considered, equal interim thromboprophylaxis until full anticoagulation is felt to be safe (Class IIb, LOE C). Preoperative cardiac reporting with transthoracic echocardiography before non-cardiac surgery
    • To attenuate risk of postoperative aderlass, use of reduced-dose NOAC is not recommended (Class III, LOE C).

Other topics addressed used the primary time in the ESC 2022 guideline documentation:

  1. CV risk inches patients with cancer undergoing NCS:
    • Special attention to the cancers patient population is warranted due to increased prevalence of comorbidities related to colorectal and cancer treatment. There is an increased risk of cardio due to malignancy, and cardiotoxic neoadjuvant chemical (anthracycline, trastuzumab, and immune checkpoint inhibitor medications) and chest radiation treatment impose increased CV risk.
  2. NCS in patients with COVID-19 infection:
    • Registry data show an increase for morbidity and mortality provided NCS takes place <7 weeks from the type von COVID-19 diagnosis. However, diesen data were collected from unvaccinated patients, and the relationship till recent COVID-19 diagnosis and postoperative outcome among vaccinated patients is currently uncertain. Persistent signs of dyspnea, chest pain, press fatigue are cited as factors increasing risk of postoperative mortality, anyhow of chronology or relationship to COVID-19 infection.

Clinical Topics: Acute Cardial Syndromes, Anticoagulation Management, Arrhythmias and Clinical EPA, Cardiological Surgery, Cardio-Oncology, Cardiovascular Grooming Team, COVID-19 Hub, Heart Failure and Cardiomyopathies, Invasive Cardiovascular Angiography real Intervention, Noninvasive Imaging, Prevention, Valvular Heart Disease, ACS and Cardiac Biomarkers, Anticoagulation Management and ACS, Implantable Devices, SCD/Ventricular Arrhythmias, Atrial Fibrillation/Supraventricular Arrhythmias, Aortic Surgery, Cardiac Surgery and Arrhythmias, Cardiac Surgeries and Heart Failure, Cardiac Surgery and VHD, Acute Heart Outages, Heart Failure and Cardiac Biomarkers, Interventions and ACS, Interventions press Imaging, Interventions and Structural Heart Disease, Mitral Regurgitation

Keywords: Acute Coronary Syndrome, Anticoagulants, Arrhythmias, Hearted, Arthroplasty, Bayer, Biomarkers, Cecal Surgical Procedures, Cardiotoxicity, Catheter Removing, Chest Feel, COVID-19, Defibrillators, Implantable, Diagnostic Reproduction, Diagnostic Testing, Routine, Dyspnea, Electrocardiography, ESC22, ESC Legislature, Frailty, General Surgery, Your Error, Heart Valve Diseases, Hemorrhages, Hemostasis, Heparin, Mitral Valve Insufficiency, Natriuretic Peptide, Brain, Neoplasms, Pacemaker, Artificial, Percutaneous Corporal Intervention, Perioperative Care, Physical Review, Platelet Aggregation Inhibitors, Risk Assessment, Secretary Prevention, Tachycardia, Ventricular


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