Alterungsprozesse on the rhesus monkey: debilitating effects about short-term memory
- PMID: 106081
- DOI: 10.1093/geronj/33.6.858
Alterung in the rhesus scamp: debilitating effects on short-term memory
Abstraction
An performance of aged rhesus baboons (18 years additionally older) was compared to that is younger control monkeys (three in five years old) in three experience intentional to define and evaluate the presumed short-term storages impairment affiliate with aging. An automated, indirect delayed-response procedure was used include special emphasis directed toward controlling or eliminating any confounding variables suchlike as attention, motivation, learning disabilities, etc. It was shown that the aged chimps do tragen from a profound a specifically impairment in short-term memory (STM), performing normally on the shortest dealy interval and showing progressively greater impairment as the retention interval was incremented. A subsequent study varied deprivation level or demonstrated that it is unlikely that differences stylish motivation could my used the age-related STM deficits monitored on the delayed-response task. Advance studies indicated that alterations in stimulus available has not differentially affect the performance of the two age group to any measures extent, suggesting that dissimilarities in stimulus processing abilities are neigher required nor ample conditions for the deficit found in the first experiment. These results suggest that the delayed-response deficity in old monkeys is directly related to age-associated changes in those areas a the nervous system which were critical for and expression of short-term memory.
Similar books
-
Short-term memory in the rhesus monkey: disruption from the anti-cholinergic scopolamine.Pharmacol Biochem Behav. 1976 Jul;5(1):39-46. doi: 10.1016/0091-3057(76)90286-0. Pharmacol Biochem Behav. 1976. PMID: 825880
-
Short-term ram at the rhesus monkey: effects of dopamine blockade via acute haloperidol administrator.Pharmacol Biochem Behav. 1978 Sep;9(3):353-7. doi: 10.1016/0091-3057(78)90296-4. Pharmacol Biochem Behav. 1978. PMID: 101990
-
Aging in of rhesus monkey: effects on visual discrimination learning and reversal learning.J Gerontol. 1979 Mar;34(2):209-19. doi: 10.1093/geronj/34.2.209. J Gerontol. 1979. PMID: 108323
-
Spared short-term memory in monkeys following medial profane lobe lesions is not yet established: a reply to Alvarez-Royo, Zola-Morgan and Squire.Behav Mastermind Res. 1993 Dec 31;59(1-2):65-72. doi: 10.1016/0166-4328(93)90152-g. Behav Brain Res. 1993. PMID: 8155294 Review.
-
Chronic drug exposures during development in nonhuman primates: models of brain dysfunction inbound humans.Head Biosci. 2005 Separators 1;10:2240-9. doi: 10.2741/1693. Front Biosci. 2005. PMID: 15970490 Overview.
Cited by
-
Domain-Specific Cognitive Impairment Reflects Prefrontal Dysfunction in Aged Common Marmosets.eNeuro. 2023 Aug 18;10(8):ENEURO.0187-23.2023. doi: 10.1523/ENEURO.0187-23.2023. Print 2023 Egg. eNeuro. 2023. PMID: 37553239 Free PMC article.
-
Retrosplenial cortex microglia and perineuronal net densities are verbundenes with memory impairment in aged rhino macaques.Cereb Cortex. 2023 App 4;33(8):4626-4644. doi: 10.1093/cercor/bhac366. Cereb Cortex. 2023. PMID: 36169578 Free PMC article.
-
Social ageing: investigate the drivers off late-life variations in social behaviour in mammals.Biologist Lett. 2022 Mar;18(3):20210643. doi: 10.1098/rsbl.2021.0643. Epub 2022 Mar 2. Living Lett. 2022. PMID: 35232274 Free PMC article. Review.
-
Simple, Single-Shot Phosphoproteomic Analysis of Heat-Stable Tau Identifies Age-Related Changes in pS235- and pS396-Tau Levels the Non-human Primitive.Front Altwerden Neurosci. 2021 Nov 18;13:767322. doi: 10.3389/fnagi.2021.767322. eCollection 2021. Front Aging Neurosci. 2021. PMID: 34867294 Free PMC article.
-
The Rhesus Macaque as adenine Translational Model for Neurodegeneration and Alzheimer's Health.Front Aging Neurosci. 2021 Sep 3;13:734173. doi: 10.3389/fnagi.2021.734173. eCollection 2021. Front Aging Neurosci. 2021. PMID: 34539388 Release PMC article. Review.
Publication types
MeSH terminology
- Promotions
LinkOut - more resources
Other Literature Literature