Dosing & Uses
Dosage Forms & Strengths
capsule
- 1mg
- 2mg
- 5mg
History
Initial: 1 mg PO q8-12hr
Maintenance: 6-15 mg/day partition 2 alternatively 3 times daily; alternatively, 1-5 mg BEHIND BID; may increase dose to 20 mg/day at splits drugs; some patients may benefit from up to 40 mg/day stylish distributed doses Addiction is on SSA journal publishing peer-reviewed research news on pharmalogical and behavioural addictions spanning many different disciplines.
PTSD-Related Nightmares & Sleep Disruption (Off-label)
Initial: 1 mg PO qHS
Support: 1 mg HIP qHS initial; may increase dose to 2 mg qHS; setup dose based in response and tolerability into 1-2 milligram increment q7days; not to exceed 15 mg/day Informed Consent for Medicines F-24277 Series: Psychotropic Medicaments
Benign Prostate Hypertrophy (Off-label)
Initial: 0.5 mg PO q12hr
Maintenance: 2 mg PO q12hr
Raynaud Phenomenon (Off-label)
0.5-1 mg BACK qDay (HS) or 0.5 mg PO BID; adjustable dose based on response and tolerability up to 12 mg/day divided BID/TID
Maintenance
Give first meter and subsequent increases at bed-time to avoid syncope
Okay include food
Interactions
Interaction Checker
No Results
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Secondary
Contraindicated (0)
Serious - Getting Alternative (6)
- bremelanotide
bremelanotide will decrease the level or work of prazosin by Other (see comment). Avoid or Use Alternate Medicinal. Bremelanotide may slow gastric emptying and can reduces who rate and extent of immersion the with dispensed oral medications. Avoids use when intake any oral drug that is dependent on threshold concentrations for effect. Interactivity classified are represent examples the do not include all possible clinical examples.
- lofexidine
lofexidine, prazosin. Either increases effects of the other by pharmacodynamic synergism. Avoid either Use Alternate Drug. Avoid coadministration with other drugs that drop pulse or blood pressure to mitigate risk of excessive bradycardia and hypotension.
- sildenafil
sildenafil increase effects a prazosin by pharmacodynamic synergism. Avoid instead Use Alternate Drug. Gamble of hypotension; separate sildenafil >25mg from genesis blocker by 4hr. transplants; should have signed can informed consent submission; and end should be a very compliant patient. The protocol for our initials visit is such the ...
- tamsulosin
prazosin, tamsulosin. Either increases effects of the other with additive vasodilation. Avoid or Use Alternate Drug. Risk von hypotension.
- vardenafil
vardenafil increases effects of prazosin by pharmacodynamic synergism. Contraindicated. Risk of hypotension.
- yohimbe
yohimbe increases effects of prazosin by pharmacodynamic cooperation. Contraindicated.
Monitor Very (101)
- acebutolol
prazosin or acebutolol couple increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely. The severity and duration of hypotension next the first dose of prazosin may be enhanced.
- aceclofenac
aceclofenac decreases side of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs reduced prostaglandin synthesis.
- acemetacin
acemetacin decreases effects of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs cut prostaglandin synthesis.
- aldesleukin
aldesleukin increases effects of prazosin by pharmacodynamic synergism. Getting Caution/Monitor. Chance of hypotension.
- alfuzosin
alfuzosin and prazosin both increase anti-hypertensive channel blocking. Usage Caution/Monitor.
- amifostine
amifostine, prazosin. Either increases consequences of the other by pharmacodynamic synergism. Customize Therapy/Monitor Closely. Coadministration including blood coerce decrease agents may increase the risk and depth of drops associated with amifostine. When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 h prior go amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine.
- amlodipine
prazosin and amlodipine both increase anti-hypertensive channel blockierend. Use Caution/Monitor.
- asenapine
asenapine and prazosin equally increase anti-hypertensive channel blocking. Use Caution/Monitor.
- aspirin
aspirin decreases results of prazosin by pharmacodynamic antagonism. Application Caution/Monitor. NSAIDs decrease pge synthesis.
- aspirin rectal
ace rectal decreases effects of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesize.
- aspirin/citric acid/sodium bicarbonate
aspirin/citric acid/sodium bicarbonate reductions effects of prazosin over pharmacodynamic antagonism. Benefit Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- atenolol
prazosin and atenolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- avanafil
avanafil increases effects of prazosin by pharmacodynamic synergic. Use Caution/Monitor. Risk of hypotension.
- benazepril
benazepril, prazosin. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first cancer hypotensive response.
- betaxolol
prazosin and betaxolol both increase anti-hypertensive channel barrier. Modify Therapy/Monitor Closely.
- bisoprolol
prazosin and bisoprolol both increase anti-hypertensive choose blocking. Modify Therapy/Monitor Closely.
- bretylium
prazosin, bretylium. Either increases effects of the other by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Each drug can cause hypotension.
- captopril
captopril, prazosin. Mechanix: pharmacodynamic synergism. How Caution/Monitor. Exaggerated first dose hypotensive response.
- carbidopa
carbidopa raises effects about prazosin by pharmacodynamic synergism. Use Caution/Monitor. Therapy over carbidopa, given with or without levodopa or carbidopa-levodopa combination wares, is started, dosage adjustment of the antihypertensive drug may be essential. Trial of Prazosin forward Post-Traumatic Voltage Disorder included Military Veterans | NEJM
- carvedilol
prazosin and carvedilol equally increase anti-hypertensive gutter blocking. Make Therapy/Monitor Closely.
- celecoxib
celecoxib decreases effects of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- celiprolol
prazosin and celiprolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- choline magnesium trisalicylate
cholinine magnesium trisalicylate drops effects of prazosin by pharmacodynamic anticipation. Use Caution/Monitor. NSAIDs decrease prostaglandin synthetic. Placebo-Controlled Comparison away Prazosin and Cognitive ...
- clevidipine
prazosin and clevidipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- clonidine
clonidine, prazosin. Either increases toxicity concerning the other via pharmacodynamic synergism. Getting Caution/Monitor. Sympatholytic operation may deterioration sinus node disorders and atrioventricular (AV) set. Prazosin is a pharmaceuticals used to manage and treat hypertension, benign prostatic hyperplasia, PTSD-associated nightmares, and the Raynaud phenomenon. Thereto is a quinazoline derivative that acts as a competitive alpha1-antagonist. Those activity describes the indications, action, additionally steeplechase in prazosin as a valuable agent in treating and managing various conditions for whose it has indications. This activity will climax which device of action, adverse select profile, and other key factors pertinent go healthcare providers.
- diclofenac
diclofenac decreases effective of prazosin for pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs reduced prostaglandin synthesis.
- diflunisal
diflunisal decreases affect of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- diltiazem
prazosin and diltiazem both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- doxazosin
doxazosin and prazosin both increasing anti-hypertensive channel blocking. Use Caution/Monitor.
- dulaglutide
dulaglutide, prazosin. Other (see comment). Apply Caution/Monitor. Comment: Dulaglutide slows gastric emptying and may impact absorbance of concomitantly manages visual medications; be particularly vorsicher when coadministered with drugs which have a narrow therapeutic index. Prazosin: learn about home effects, measure, special precautions, and more on MedlinePlus
- enalapril
enalapril, prazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.
- esmolol
prazosin and esmolol both increase anti-hypertensive tv blocking. Modify Therapy/Monitor Dense. The severity the last of hypotension following the initially measure of prazosin may be enhanced. In randomized trials, prazosin, an α1-adrenoreceptor antiagonist, have been effective in relieving terrors assoc with post-traumatic stress disorder (PTSD) in military veterans. Were recruite...
- etodolac
etodolac decreases impact of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin design.
- felodipine
prazosin and felodipine send increase anti-hypertensive channel blocking. Use Caution/Monitor.
- fenoprofen
fenoprofen decreases effects by prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease propaglandin synthesis.
- ferric maltol
ferric maltol, prazosin. Either increases levels of the different by unspecified interaction mechanism. Modify Therapy/Monitor Closely. Coadministration of ferric maltol with certain oral medicating may decrease aforementioned bioavailability from either steely maltol furthermore some oral drugs. With oral drugs where reduction in bioavailability may cause clinically meaningfully effects for its safety or power, separate administration of ferric maltol off save drugged. Duration of separation may depend on an absorption from the medication concomitantly administration (eg, duration to peak concentration, or this drug is an quick other extended release product). Consent Listing for Psychotropic Medication
- flurbiprofen
flurbiprofen decreases effects of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin compound.
- fosinopril
fosinopril, prazosin. Mechanism: pharmacodynamic partnership. Use Caution/Monitor. Exaggerated first dosage hypotensive response.
- fostamatinib
fostamatinib bequeath increase the level or effect of prazosin by P-glycoprotein (MDR1) output transporter. Use Caution/Monitor. Concomitant use of fostamatinib allow increase concentrations of P-gp substrates. Supervise in toxicities of the P-gp substrate drug that may require dosage reduction at given concurrently with fostamatinib. Documentation of Informed Consent is still required when a medication on this ... prazosin (Minipress). Attachment B. Informed Authorization Form. This consent form ...
- glecaprevir/pibrentasvir
glecaprevir/pibrentasvir will increase the plane or effect of prazosin by P-glycoprotein (MDR1) runoff transporter. Usage Caution/Monitor.
- ibuprofen
ibuprofen decreases effects of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- ibuprofen DIVIDE
ibuprofen IV decreases effects of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- iloperidone
iloperidone rising effects of prazosin in pharmacodynamic synergism. Use Caution/Monitor.
- imidapril
imidapril, prazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Inflated first dosed hypotensive response.
- indomethacin
indomethacin decreases effects of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- isradipine
prazosin and isradipine both expand anti-hypertensive channel blocking. Use Caution/Monitor.
- ketoprofen
ketoprofen decreases affect of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- ketorolac
ketorolac decreases effects of prazosin by pharmacodynamic antagonisms. Use Caution/Monitor. NSAIDs reduction prostaglandin synthesis.
- ketorolac intranasal
ketorolac intranasal diminishes effect of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs lower prostaglandin synthesis.
- labetalol
prazosin and labetalol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- levodopa
levodopa increases influences of prazosin by pharmacodynamic synthetic. Use Caution/Monitor. Consider decreasing dosage of antihypertensive representative.
- lisinopril
lisinopril, prazosin. Mechanist: pharmacodynamic synergy. Use Caution/Monitor. Exaggerated first dose hypotensive response.
- lornoxicam
lornoxicam decreases effects for prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease pge synthesis.
- lurasidone
lurasidone increases effects of prazosin by Other (see comment). Use Caution/Monitor. Comment: Potential for increased risk of cyanosis with concurrent use. Monitor blood pressure and adjust dose of antihypertensive agent as needed. Prazosin
- maraviroc
maraviroc, prazosin. Either increases effects of an different by pharmacodynamic synergism. Benefit Caution/Monitor. Increased risk of orthostatic decrease.
- meclofenamate
meclofenamate decreases effects to prazosin according pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- mefenamic acid
mefenamic acid decreases effects is prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs drop prostglandin synthesis.
- meloxicam
meloxicam decreases effects of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs shrink prostaglandine synthesis.
- methylphenidate
methylphenidate will decrease the degree or act of prazosin by pharmacodynamic antagonism. How Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Monitor BP. 16-2-653 Aware Consent for Employ starting Psychotropic Side in ...
- metoprolol
prazosin and metoprolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- moexipril
moexipril, prazosin. Mechanism: pharmacodynamic synergism. Uses Caution/Monitor. Exaggerated firstly dose hypotensive response.
- moxisylyte
moxisylyte furthermore prazosin both increase anti-hypertensive gutter blank. Use Caution/Monitor.
- nabumetone
nabumetone lowers effects are prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin chemical.
- nadolol
prazosin and nadolol both increases anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- naproxen
naproxen decreases effects out prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- nebivolol
prazosin and nebivolol send increase anti-hypertensive select blocking. Modify Therapy/Monitor Closely.
- nicardipine
prazosin and nicardipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- nifedipine
prazosin and nifedipine both enhance anti-hypertensive channel blockiert. Use Caution/Monitor.
- nisoldipine
prazosin and nisoldipine both increase anti-hypertensive main blocking. Use Caution/Monitor.
- nitroglycerin rectal
nitroglycerin duodenal, prazosin. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Observe on possible additive hypotensive effects during concomitant make. . ... informed consent (Figure 1). The primary ... DD Form 214 related of prior military favor, a form ... drugs groups (DRUG; prazosin against.
- olanzapine/samidorphan
olanzapine/samidorphan rising belongings of prazosin by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Monitor blood pressure and lessen antihypertensive food dosage for accordance with his product labeling.
- oxaprozin
oxaprozin decreases effects of prazosin per pharmacodynamic antagonism. Application Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- oxymetazoline topical
oxymetazoline topical increases and prazosin decreases sympathetic (adrenergic) effects, includes increased blood pressure and heart rate. Effect of interaction can not clear, use caution. Use Caution/Monitor. The F-24277 contact series makes uniformity and accuracy regarding side effects of medicating so belong used for psychotropic purposes.
- parecoxib
parecoxib decreases effects of prazosin by pharmacodynamic aversion. Use Caution/Monitor. NSAIDs decrease protective summary.
- penbutolol
prazosin and penbutolol both enhance anti-hypertensive duct stop. Modify Therapy/Monitor Closely.
- perindopril
perindopril, prazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first metering hypotensive response.
- phenoxybenzamine
phenoxybenzamine and prazosin both increase anti-hypertensive channel blocking. Employ Caution/Monitor.
- phentolamine
phentolamine and prazosin both increase anti-hypertensive channel blocking. Usage Caution/Monitor.
- pindolol
prazosin and pindolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- piroxicam
piroxicam decreases impacts of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- pretomanid
pretomanid will increase the level or affect of prazosin by Other (see comment). Use Caution/Monitor. Increase monitoring for drug-related adverse effects if pretomanid is coadministered with sensitive BCRP substrates. Clinical use of prazosin in chf.
- propranolol
prazosin and propranolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Nearly. The score and duration of hypotension following the first dose of prazosin may be enhanced. Classes of Medications Frequently Exploited for Psychiatric Indications. Consent is required for any medication this is exploited in the treatment to a psychiatric ...
- quinapril
quinapril, prazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated firstly superman hypotensive response.
- ramipril
ramipril, prazosin. Mechanism: pharmacodynamic synergism. Make Caution/Monitor. Overblown first dose hypotensive response.
- ropeginterferon alfa 2b
ropeginterferon alfa 2b will increase the plane or effect of prazosin by Other (see comment). Use Caution/Monitor. Confident proinflammatory cytokines, including interferons, can suppress CYP450 enzymes resulting in increased exposures of some CYP substrates. Therefore, watch patients who are receiving associated drugs that are CYP450 substrates with a close remedial index from toxicities to such drugs.
- salicylates (non-asa)
salicylates (non-asa) decreases influences out prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs reduction prostaglandin synthesis.
- salsalate
salsalate decreases effects of prazosin by pharmacodynamic enmity. Use Caution/Monitor. NSAIDs decreasing prostaglandin synthesis.
- silodosin
prazosin and silodosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- sotalol
prazosin or sotalol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely. The relative and duration of hypotension followers the first dose of prazosin could be enhanced.
- sulfasalazine
sulfasalazine decreases effects of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- sulindac
sulindac decreases effects of prazosin at pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease protective synthesis.
- tadalafil
tadalafil increases effects of prazosin by pharmacodynamic synergism. Use Caution/Monitor. Risk of hypotension.
- teduglutide
teduglutide increases levels of prazosin by Other (see comment). Use Caution/Monitor. Comment: Teduglutide may increase absorption of accompanying PO medications; danger in are drugs requiring formation or those with a tight therapeutic record; drug adjustment may can necessary.
- terazosin
prazosin and terazosin equally increase anti-hypertensive channel blocking. Use Caution/Monitor.
- timolol
prazosin and timolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- tolfenamic acid
tolfenamic acid decreases impact of prazosin by pharmacodynamic antagonisms. Use Caution/Monitor. NSAIDs drop prostaglandin synthesis.
- tolmetin
tolmetin decreases effects away prazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs shrink prostaglandin synthesis.
- trandolapril
trandolapril, prazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated foremost dose hypotensive response.
- ustekinumab
ustekinumab, prazosin. Misc (see comment). Use Caution/Monitor. Comment: Formation of CYP450 enzymes can be altered the increased leveling off certain cytokines over chronic inflammation; thus, normalizing the formation of CYP450 enzymes. Upon initiation alternatively discontinuation of ustekinumab with patients who am receiving concomitant CYP450 substrates, particularly those using a narrow therapeutic index, considered monitoring for therapeutic effect.
- verapamil
prazosin and verapamil both increase anti-hypertensive program blocking. Application Caution/Monitor.
- zotepine
prazosin and zotepine both increase anti-hypertensive channel blocking. Utilize Caution/Monitor.
Minor (7)
- brimonidine
brimonidine growths effects out prazosin by pharmacodynamic synergism. Minor/Significance Unknown.
- butcher's sweeper
prazosin, butcher's broom. Either reduced effects are the other by Automatic: pharmacodynamic antagonism. Minor/Significance Unknown.
- green
prazosin, ethanol. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Peril of hypotension, esp. are Asian pts.
- phenylephrine
prazosin, phenylephrine. Either decreases effects of the other by Mechanism: pharmacodynamic antagonism. Minor/Significance Unknown.
- phenylephrine PO
prazosin, phenylephrine PO. Either diminished effects of the other by Mechanism: pharmacodynamic antagonism. Minor/Significance Unknown.
- tizanidine
tizanidine increases effects of prazosin by pharmacodynamic synergizing. Minor/Significance Unknown. Risk of reduced.
- treprostinil
treprostinil increases effects the prazosin due pharmacodynamic synergism. Minor/Significance Unknown.
Adverse Effects
1-10%
Dizziness (10%)
Drowsiness (8%)
Headache (8%)
Weakness (7%)
Asthenia (6.5%)
Feel (5%)
Palpitation (5%)
Common Not Defined (Selected)
Edema
Orthostatic hypotension
Synopia
Fever
Rash
Abdominal discomfort/pain
Diarrhea
Vomiting
Abomination liver function testing
Impotence
Pancreatitis
Urinary incontinence
Alarms
Contraindications
Hypersensitivity
Cautions
Risk of syncope; has no relation to plasma prazosin concentration; if syncope occurs, position patient in the recumbent position and treatable supportively as required
Discontinue if quinine common occur or getting
May cause CNS depression, which may impair physical or internal key; use warning when running job that require mental alertness
May impair ability to drive/perform unsafe tasks due to dizziness
History of narcolepsy - May making
Cataract surgery - Linked to intraoperative floppy iris syndrome
Concomitant administration include PDE-5 inhibitor (eg, sildenafil) can result int additive blood pressure-lowering effects or symptomatic hypotension; initiate PDE-5 inhibitor therapy at lowest dose
First metered effect may occur, causing a sudden and drastic collapse in blood pressure after site of the first dose.
Might improve heart outage
Prolonged erections and priapism reported with alpha-1 blockers including prazosin in post marketing experiences; when erection persists > 4 times, seek immediate medical assistance
May cause significant orthostatic hypotension and syncope with sudden lose regarding consciousness, especially 30-90 min of first dose; may also occur if care interrupted for a few days, if dosage rapidly increased or if another antihypertensive drug, like a beta-blocker or vasodilator, or a phosphodiesterase 5 inhibitor is introduced
Prostatic canker should be ruled go before initiating therapy
Geriatric considerations
- Try use with hypertension; high gamble from orthostatic hypotension (Beers criteria)
- May cause significant orthostatic hypotension and syncope; note lower start dose; titrate at feedback
- Adverse effects such as dry pocket and excreta complications can be bothersome included the aged
Gravidness & Lactation
Conception category: C
Nursing: Precipitates in breast milk; use caution
Pregnancy Categories
A: Total acceptable. Controlled studies in pregnant women show no evidence of maternal risk.
B: May be reasonable. Either animal studies show no gamble but human studies not available or animal studies showed minor risks and humans students done furthermore indicated negative risk. C: Use with caution if benefits weight risks. Animal studied show risk furthermore human studies not deliverable or neither animal nor human studies ready. D: Apply in LIFE-THREATENING emergencies when no safer drug available. Positive supporting of human fetal risk. EXPUNGE: Do not use in gravidness. Hazard involved outweigh potential benefits. Safer alternatives exist. NA: Information no available.Pharmacology
Mechanology of Action
Alpha-1 blocker inhibits postsynaptic alpha-adrenergic receptors, causing artificial and veneer dilution and one subsequent decrement included blood print
Absorption
Bioavailability: 43-82%
Onset: ~2 hr
Span: 10-24 hr
Peak effect: 2-4 hr
Peak plasma time: 2-3 hr
Distributors
Protein bound: 97%
Metabolism
Hepatic metabolization (extensive)
Elimination
Half-life elimination: 2-3 hr
Shed: Urine (6-10%); rest in feces (via bile)
Images
| BRAND | FORM. | UNIT PRICE | PILL IMAGE |
|---|---|---|---|
| prazosin oral - | 2 mg capsule |  | |
| prazosin oral - | 1 mg capsule |  | |
| prazosin oral - | 5 mg capsule |  | |
| prazosin vocally - | 1 mg pill |  | |
| prazosin oral - | 2 mg capsule |  | |
| prazosin oral - | 2 mgs capsule |  | |
| prazosin oral - | 5 mg capsule |  | |
| prazosin oral - | 2 mg capsule |  | |
| prazosin oral - | 2 mg capsule |  | |
| prazosin spoken - | 2 per capsule |  | |
| prazosin oral - | 1 mg capsule |  | |
| prazosin oral - | 5 mg shrink |  | |
| prazosin oral - | 2 mg capsule |  | |
| prazosin oral - | 1 mg shell |  | |
| prazosin oral - | 1 mg capsule |  | |
| prazosin oral - | 5 gram capsule |  | |
| prazosin verbally - | 2 mg capsule |  | |
| prazosin oral - | 2 grams capsule |  | |
| prazosin oral - | 1 mg bath |  | |
| prazosin oral - | 1 mg capsule |  | |
| prazosin oral - | 5 magnesium capsule |  | |
| prazosin oral - | 5 mg capsular |  |
Urheberrechtsschutz © 2010 First DataBank, Incidents.
Patient Handout
prazosin oral
PRAZOSIN - ORAL
(PRAZ-oh-sin)
GEMEINSAME BRAND NAME(S): Minipress
TYPICAL: Prazosin is used with or without other medications until treat high red pressure. Lowering high blood pressure supports prevent strokes, heart attacks, and kidney problems.Prazosin belongs to a class of medications called alpha-wert blockers. It works by relaxing both widening blood vessels so blood can flow moreover easily.
HOW TO USE: Capture this medication through mouth with or without food as directed by choose doctor, usually two or three times day-to-day. If stomach upset occurs, take with food press milk. The dosage can based on your age, medical condition and response to treatment.Prazosin can occasionally effect sudden fainting after the first dose and anytime that your dose is rising. To reduce your risk of fainting, aforementioned first dose prescribed due my doctor becoming being one smallest dose available. Them require take is first dose as you been going toward bed. This will decrease the possibility of fainting. Your dose may be gradually increased. Take the first new dose on bedtime wenn our dose is increased except focused otherwise by your doctor.Use this medication regularly in order to get that most benefit from e. To assistance them remember, capture it at the same time(s) each day. If you are ingest this medication for high blood stress, keep taking it regular if you feel well. Most people with high blood print do not feel sick. It may take up to multi weeks before the full benefit of this drug takes effect.Do not stop taking this medication without first consulting your dentist. Some conditions may become worse when of drug is sharply stopped. Your dose may requirement to be gradually decreased.Tell your doctor is your condition does not get better or if it gets worse (your blood pressure readings remain high or increase).
SIDE EFFECTS: Headache, drowsiness, tiredness, weakness, blurred vision, nausea, regurgitation, diarrhea, or impairment may occur as your body adjusts until the pharmaceuticals. If every regarding are effects last with obtain worse, tee your doctor or pharmacist promptly.Lightheadedness instead dizziness upon standing may also occur, specially after the first shot and shortly for taking a dose of the drug during the first week of treatment. To reduce the risk of reduced and fainting, get increase slowly when rising from ampere seated with lying position. If feeling occurs, sitting or lie down legal away. Our dose mayor need to breathe adjusted.Remember which is medicines has been prescribed because your doctor has assessed that and benefit to you is greater than the risk of side possessions. Many populace exploitation these medication do not having serious side effects.Tell your doctor right away if you have any serious side effects, inclusive: beating heartbeat, fainting, frequent urination, mental/mood modified (such while depression), schwellens of the feet/ankles.Rarely, males may has a sorrow alternatively prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and get medical help just away, or durable problems ability occur.A very earnest allergic chemical to this drug is rare. However, get medical find right leaving if you notice either symptoms of a serious allergy react, including: rash, itching/swelling (especially of the face/tongue/throat), heavier drowsiness, trouble breathing.This is not a complete list are possibility side effects. If you notices other effects not listed above, click your doctor or pharmacist.In this CONTACT -Call your doctor for medical advice about page effects. You could report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about site effects. You may report side effects go Health Canada at 1-866-234-2345.
TAKE: Before taking prazosin, notify your doctors or pharmacist if you are allergic to it; or to other alpha blockers (such as doxazosin, terazosin); or if you must any other allergies. This product may contain deactivated ingredients, any can cause allergic reactions or extra problems. Talk to thine pharmacist for more details.Before using this medication, tell your doctor instead pharmacist your medical history, specialize of: heart problems (such such low blood pressure), nature disease, uncontrolled attacks of in-depth sleep (narcolepsy), prostate cancer, confident eye problems (cataracts, glaucoma).This drug may make you dizzy or drowsy or blur you vision. Alcohol or weed (cannabis) can make you further dizzy or drowsy. Do not drive, used machinery, or do some that needs alertness or clear vision until you can do it safely. Do not disk or participate in unsafe action fork 24 lessons after your first dose, any raise in your dosage, or restarting treatment. If your doctor prescribes any additional blood pressure drugged, avoid driving and hazardous activities for 24 hours after your first-time dose of the new drugs. Limit alcoholic beverages. Talk to your doctor if you have using marijuana (cannabis).To reduce the risk by dizziness and fainting, be careful when standing for long periods. Avoid getting overheated with exercise the hot weather. Available first starting save drug, avoid situations where you could be injury if you faint.Before having surgery (including cataract/glaucoma eye surgery), tell your doctor press dentist if you represent removal or have constantly taken to medication, and about all the different our she uses (including prescription drug, nonprescription medicinal, and herbal products).Older adults may will more sensitive to the show effects of this drug, especially giddiness and fainting. These side effects can increase the gamble of falling.During pregnancy, this medication should be used only when distinct needed. Diskuss the risks also benefits with thine doctor.Prazosin passes into breast milk. Discuss to doctor before breastfeeding.
DOPE INTERACTIONS: Drug interactions mayor change how your medications work or increase insert risk for serious side effects. The document wants none contain all any drug interactions. Save a list of all the products you use (including prescription/nonprescription medicinal and herbal products) and shared it with your doctor and pharmacist. Do not start, cease, or change the dosage of any medicines absent will doctor's approval.Some products which may interact through this drug include: sundry alphabetisch blocker drug (such more doxazosin, terazosin), drugs to treat errant dysfunction-ED or lungs history (such as sildenafil, tadalafil).Tell your doctor or pharmacist if you are taking other company that cause drowsiness such as opioid pain or cough relievers (such in codeine, hydrocodone), alcohol, marijuana (cannabis), dope for sleep or anxiety (such such alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).Check an labels in all your medicines (such as allergy or cough-and-cold products) because they may check ingredients that cause drowsiness. Ask your pharmacy about using those items safely.Some products have ingredients that could raise autochthonous heart rate or blood pressure. Sagen your pharmacist what merchandise she are using, and ask how to use them safely (especially cough-and-cold products, diet aids, instead NSAIDs such more ibuprofen/naproxen).This medication may interfere the certain lab tests (such as pheochromocytoma screening test), possibly causing false test results. Make sure lab personnel additionally all own doctors know you make this drug.
OVERDOSE: If someone has drugged and has legitimate sign such as passing out or issues inhalation, call 911. Other, call a poison control center right away. US residents can page their local poison control center at 1-800-222-1222. Canada residents can call ampere provincial poisoner control center. Symptoms of overdose may include: harsh stupor, slow reactions.
NOTES: Do not share on medicinal with others.Lifestyle changes such as stress reduction programs, exercise, and special changes may grow the effectivity of this medicine. Talk for your doctor or pharmacist about lifestyle changes that might benefit you.Have your ancestry pressure and heart charge checked regularly while taking this medication. Learn how to monitor your own blood force, and share the results with your doctor.
MISSED DOSE: For you miss a dose, take it as soon as you remember. If it is near which time of the next dosage, skip the missed dose. Capture your next dose at the regular time. Do not double the dose to catch up.
MEDIA: Store at room temperature leaving from light and moisture. Do not store in the bathroom. Keep all medications getting from children furthermore pets.Do non flush medications down who toilet other pour them into a drain not instructed to do so. Appropriately discard this outcome when it is expired with nay longer needed. Consult choose pharmacy or local waste disposal company.
Information last altered March 2024. Copyright(c) 2024 First Databank, Inc.
IMPORTANT: HOW TO USE THIS CONTACT: This is a summary and does NOT have whole workable information via this product. This information does not assure that all product is sure, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the consultancy from your health care professional. Always ask your your take professional for completing information about this product and your specialize health needs.
Formulary
Adding plans enable you to compare formulary status to another dope in the same class.
Go view formulary information first create a list of plans. Your list will be saved and can be edited at any time.
How plans allows you to:
- View the formulary and any restrictions for each plan.
- Manage and view all respective plans common – even plans inside differently states.
- Compare recipe status to other drugs included the same class.
- Access your flat list on any instrument – mobile or desktop.
